CAR-T 靶点蛋白

嵌合抗原受体修饰T细胞(CAR-T)治疗是一种新型的免疫治疗方法,已在多种血液系统恶性肿瘤的治疗中取得了显著的成功。
CAR-T疗法的理念是让免疫系统攻击癌细胞。简而言之,患者的T细胞被分离出来并通过基因工程表达一种嵌合抗原受体(CAR),它能识别特定的肿瘤相关抗原(TAA),如CD19,一种细胞表面蛋白,在恶性B细胞上均匀而强烈地表达。两种新的FDA批准的CD19特异性药物KymriahTM和YescartaTM表明了TAA在CAR-T细胞治疗研究中的重要性。
基于特色的SAMSTM平台,Kactus开发出一系列覆盖多个CAR-T细胞治疗靶点的重组蛋白,包括一些难以表达的蛋白,如CD19和BCMA。
Kactus Biosystems提供多种类型的高活性CAR-T靶点抗原蛋白,包括定点标记蛋白、荧光标记蛋白、生物素标记蛋白等,可灵活满足CAR-T阳性率检测等不同研发需求。
数据展示

Human FITC Compatible CD19

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Use Human CD19-FITC Compatible protein to detect the expression rate of Anti-CD19-CAR positive cells. Non-transfected 293T cells and FITC-labeled protein control were used as negative control.

PE-Labeled Human EGFR VIII

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293T-CAR Cells were incubated with PE-Labeled Human EGFR VIII, His Tag and PE-labeled protein control. Non-transfected 293T cells and PE-labeled protein control were used as negative control.

Biotinylated Human MSLN

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Anti-MSLN CAR-293T cells were incubated with Biotinylated human MSLN-hFc-Avi Tag. Non-transfected 293T cells and Fc-labeled protein control were used as negative control. SA-FITC was used to evaluate the binding activity of Biotinylated Human MSLN.
产品列表
货号 名称 种属 标签 表达体系
CD1-HM119F FITC-compatible CD19 Protein Human C-His Expi293 立即询价
BH7-HM173 Human B7-H3/CD276 Protein Human C-His Expi293 立即询价
BCM-HM117 Human BCMA/TNFRSF17 Protein Human C-His-Avi Expi293 立即询价
MSL-HM480F FITC-Labeled Human MSLN/Mesothelin Protein Human C-His-Avi Expi293 立即询价
MSL-HM280F FITC-Labeled Human MSLN/Mesothelin Protein Human C-hFc Expi293 立即询价
SIG-HM122 Human Siglec-2/CD22 Protein Human C-His Expi293 立即询价
CD3-HM430 Human CD30/TNFRSF8 Protein Human C-His-Avi Expi293 立即询价
CD3-HM433 Human Siglec-3/CD33 Protein Human C-His-Avi Expi293 立即询价
CD4-HM401 Human CD4/LEU3 Protein Human C-His-Avi Expi293 立即询价
CD7-HM401 Human CD7 Protein Human C-His-Avi Expi293 立即询价
MSL-HM580B Biotinylated Human MSLN/Mesothelin Protein Human C-hFc-Avi Expi293 立即询价
EG8-HM154 Human EGFR VIII Protein Human C-His-Avi Expi293 立即询价
EGF-HM401 Human EGFR/HER1 Protein Human C-His-Avi Expi293 立即询价
EG8-HM154F FITC-Labeled Human EGFR VIII Protein Human C-His-Avi Expi293 立即询价
EG8-HM154P PE-Labeled Human EGFR VIII Protein Human C-His-Avi Expi293 立即询价
FAP-HM101 Human FAP Protein Human N-His Expi293 立即询价
FOL-HM4R1 Human FOLR1 Protein Human C-His-Avi Expi293 立即询价
GPC-HM131 Human GPC3/Glypican 3 Protein Human C-His Expi293 立即询价
HER-HM402 Human Her2/ErbB2 Protein Human C-His-Avi Expi293 立即询价
HER-HM403 Human Her3/ErbB3 Protein Human C-His-Avi Expi293 立即询价
MSL-HM480 Human MSLN/Mesothelin Protein Human C-His-Avi Expi293 立即询价
NEC-HM404 Human Nectin-4 Protein Human C-His-Avi Expi293 立即询价
NKG-HM42D Human NKG2D/CD314 Protein Human N-His-Avi Expi293 立即询价
PSM-HM110 Human PSMA/FOLH1 Protein Human N-His Expi293 立即询价
ROR-HM401 Human ROR1 Protein Human C-His-Avi Expi293 立即询价
SMF-HM407 Human SLAMF7/CRACC/CD319 Protein Human C-His-Avi Expi293 立即询价
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