STP-HM02V-100μg / 询价
STP-HM02V-100μgx5 / 询价
STP-HM02V-100μgx10 / 询价
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Human STEAP2 VLP
Recombinant Human STEAP2 VLP is expressed from HEK293.It contains Met1-Met490 (It may have cross reaction with anti-His antibody) [Accession | Q8NFT2-1].
The target protein has a predicted MW of 66.72 kDa.
> 95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
STEAP2, also known as the six transmembrane protein of prostate 1 (STAMP1), is located on chromosome 7q21.13, contains 6 exons and 5 introns, and encodes for a 490 aa long protein with an estimated molecular weight of 56.1 kDa. STEAP2 has been suggested to play a role in protein sorting and secretory pathways, as it shuttles to the Golgi organelle and trans-Golgi network. STEAP2 is significantly overexpressed in prostate cancer when compared to normal healthy tissue.
PUMPCn; PCANAP1; STAMP1; STEAP 2; STMP; IPCA-1
Jones LA, Conway GE, Nguyen-Chi A, Burnell S, Jenkins GJ, Conlan RS, Doak SH. Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer. Cell Mol Biol (Noisy-le-grand). 2023 Apr 30;69(4):179-187. doi: 10.14715/cmb/2023.69.4.28. PMID: 37329528.
