IL5-HE015-100μg / 询价
IL5-HE015-500μg / 询价
IL5-HE015-500μgx2 / 询价
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关联产品
Human IL-2 R beta&IL-2 R gamma Protein
Human IL-2 R beta/CD122 Protein
Cynomolgus IL-2 R beta/CD122 Protein
Biotinylated Cynomolgus IL-2 R beta/CD122 Protein (Primary Amine Labeling)
Human IL-15RA/IL-15 R alpha/CD215 Protein
Human IL-15RA/IL-15 R alpha/CD215 Protein
Biotinylated Human IL-15RA/IL-15 R alpha/CD215 Protein
Human IL-2 R beta/CD122 Protein
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Human IL-15 Protein
Recombinant Human IL-15 Protein is expressed from E.coli without tag.It contains Asn49-Ser162 [Accession | P40933].
The protein has a predicted MW of 12.8 kDa same as Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 0.05 EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NACI (pH 7.5). Normally 8% mannitol is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human IL-15 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-15 is greater than 95% as determined by SEC-HPLC.
Immobilized Human IL-15, No Tag at 2 μg/ml (100 μl/Well) on the plate. Dose response curve for Human IL-15RA, His Tag with the EC50 of 15.4 ng/ml determined by ELISA.
Human IL-2 R beta, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-15, No Tag with an affinity constant of 5.9 nM as determined in SPR assay (Biacore T200).
Measured in a cell proliferation assay using CTLL-2 cells. The ED50 for this effect is 0.1 - 0.3 ng/mL. The specific activity of recombinant human IL-15 is > 1 × 10^7 units/mg, which is calibrated against the human IL-15 reference standard (NIBSC code: 95/554) (QC Test).
Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseases. IL-15 is a cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA.
L15; IL-15; IL-15MGC9721; Interleukin-15
(1) Rautela J , Huntington N D. IL-15 signaling in NK cell cancer immunotherapy [J]. Current Opinion in Immunology, 2017, 44:1-6.
