IL2-DM122 | 价格

IL2-DM122-100μg / 询价

IL2-DM122-500μg / 询价

IL2-DM122-500μgx2 / 询价

Canine IL-22 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Canine IL-22 Protein is expressed from HEK293 with His tag at the C-terminus.
It contains Leu34-Val179 [Accession | E2R2K7].

分子量大小(Molecular Weight)

The protein has a predicted MW of 18.43 kDa. Due to glycosylation, the protein migrates to 32-42 kDa based on Tris-Bis PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Canine IL-22 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
ELISA Data
Immobilized Canine IL-22, His Tag at 5μg/ml(100μl/well) on the plate. Dose response curve for Human IL-22R alpha 1, hFc Tag with the EC50 of 40.0ng/ml determined by ELISA (QC Test).
背景(Background)

The cytokine interleukin-22 (IL-22) is a critical regulator of epithelial homeostasis. It has been implicated in multiple aspects of epithelial barrier function, including regulation of epithelial cell growth and permeability, production of mucus and antimicrobial proteins (AMPs), and complement production.

分子别名(Synonyms)

Interleukin-22; IL-22; Cytokine Zcyto18; IL-TIF; IL-D110; TIFa; TIFIL-23; ZCYTO18; IF2B1; Interferon 2B1;IL22; TIFIL23;IL 22; Interleukin 22

文献(References)

(1) Keir M, Yi Y, Lu T, Ghilardi N. The role of IL-22 in intestinal health and disease. J Exp Med. 2020 Feb 13;217(3):e20192195. doi: 10.1084/jem.20192195. PMID: 32997932; PMCID: PMC7062536.