ILA-MM117-100μg / 询价
ILA-MM117-500μg / 询价
ILA-MM117-500μgx2 / 询价
Mouse IL-17A/CTLA-8 Protein
Recombinant Mouse IL-17A/CTLA-8 Protein is expressed from HEK293 with His tag at the N-terminus.It contains Ala26-Ala158 [Accession | Q62386].
The protein has a predicted MW of 16.07 kDa. Due to glycosylation, the protein migrates to 18-24 kDa and 25-28 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1 EU per μg by the LAL method.
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
CTLA-8; IL17; IL17A; IL-17CTLA-8; interleukin 17A
(1)Gaffen S L. An overview of IL-17 function and signaling[J]. Cytokine, 2008, 43(3):0-407.
