TSP-HM401F | 价格

TSP-HM401F-100μg / 询价

TSP-HM401F-500μg / 询价

TSP-HM401F-500μgx2 / 询价

FITC-Labeled Human TSLP Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant FITC-Labeled Human TSLP Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.
It contains Tyr29-Gln159 [Accession | Q969D9-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 17.8 kDa. Due to furin cleavage site, the protein migrates to 12 kDa & 25-30 kDa based on Bis-Tris PAGE result.

波长(Wavelength)

Excitation Wavelength: 490 nm

Emission Wavelength: 520 nm

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

FITC-Labeled Human TSLP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of FITC-Labeled Human TSLP is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized FITC-Labeled Human TSLP, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-TSLP Antibody, hFc Tag with the EC50 of 15.4ng/ml determined by ELISA (QC Test).

背景(Background)

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.

分子别名(Synonyms)

thymic stromal lymphopoietin; TSLP

文献(References)

(1)Corren J , Parnes J R , Wang L , et al. Tezepelumab in Adults with Uncontrolled Asthma[J]. New England Journal of Medicine, 2017, 377(10):936-946.