TSP-HM401F | 价格

TSP-HM401F-100μg / 询价

TSP-HM401F-500μg / 询价

TSP-HM401F-500μgx2 / 询价

FITC-Labeled Human TSLP Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant FITC-Labeled Human TSLP Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.
It contains Tyr29-Gln159 [Accession | Q969D9-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 17.8 kDa. Due to furin cleavage site, the protein migrates to 12 kDa & 25-30 kDa based on Bis-Tris PAGE result.

波长(Wavelength)

Excitation Wavelength: 490 nm

Emission Wavelength: 520 nm

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 1 EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 6 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

FITC-Labeled Human TSLP on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of FITC-Labeled Human TSLP is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized FITC-Labeled Human TSLP, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-TSLP Antibody, hFc Tag with the EC50 of 15.4ng/ml determined by ELISA (QC Test).

背景(Background)

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.

分子别名(Synonyms)

thymic stromal lymphopoietin; TSLP

文献(References)

(1)Corren J , Parnes J R , Wang L , et al. Tezepelumab in Adults with Uncontrolled Asthma[J]. New England Journal of Medicine, 2017, 377(10):936-946.