MHC-HM436T-100μg / 询价
MHC-HM436T-500μg / 询价
MHC-HM436T-500μgx2 / 询价
|
表达区间及表达系统(Source)
|
Recombinant Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLPQLCTEL peptide [Accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&KLPQLCTEL]. |
|
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reduced (N) condition based on Bis-Tris PAGE result. |
|
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
|
内毒素(Endotoxin)
|
Less than 1 EU per μg by the LAL method. |
|
制剂(Formulation)
|
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
|
重构方法(Reconstitution)
|
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions. |
|
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLPQLCTEL peptide [Accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&KLPQLCTEL].
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reduced (N) condition based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.
Human papillomavirus type 16; HPV16; E6;
Zhang L, Lai Y, Sun Y, Xu B, Qiang X, Zhou X, Wang T. HPV16 E6 regulates the proliferation, invasion, and apoptosis of cervical cancer cells by downregulating miR-504. Transl Cancer Res. 2020 Dec;9(12):7588-7595. doi: 10.21037/tcr-20-2913. PMID: 35117358; PMCID: PMC8799100.
MHC-HM436T-100μg / 询价
MHC-HM436T-500μg / 询价
MHC-HM436T-500μgx2 / 询价
| 货号* | 规格* | 名称 | 数量* | |
|---|---|---|---|---|
| 货号* | 形态* | 批号* | |
|---|---|---|---|
| 货号* | 形态* | 批号* | |
|---|---|---|---|
| 货号* | 批号* | |
|---|---|---|
| 货号* | 规格* | 批号* |
|---|---|---|
| Buffer 货号* | Buffer 规格* | Buffer 批号* |
|---|---|---|
| 货号* | 批号* | |
|---|---|---|