MCM-MM101 | 价格

MCM-MM101-100μg / 询价

MCM-MM101-500μg / 询价

MCM-MM101-500μgx2 / 询价

Mouse MADCAM1 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Mouse MADCAM1 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Gln22-Ser364 [Accession | Q61826-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 32.5 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Mouse MADCAM1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Mouse MADCAM1 is greater than 95% as determined by SEC-HPLC.

背景(Background)

Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of our study was to determine whether selected single nucleotide polymorphisms (SNPs) of the MADCAM1 gene are associated with development of serious complications after aHSCT.

分子别名(Synonyms)

MAdCAM-1; MADCAM1; MACAM1

文献(References)

(1) Ambruzova Z, Mrazek F, Raida L, Stahelova A, Faber E, Indrak K, Petrek M. Possible impact of MADCAM1 gene single nucleotide polymorphisms to the outcome of allogeneic hematopoietic stem cell transplantation. Hum Immunol. 2009 Jun;70(6):457-60. doi: 10.1016/j.humimm.2009.03.008. Epub 2009 Mar 12. PMID: 19286444.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.