ILR-MM15R | 价格

ILR-MM15R-100μg / 询价

ILR-MM15R-500μg / 询价

ILR-MM15R-500μgx2 / 询价

Mouse IL-5 R alpha/CD125 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Mouse IL-5 R alpha/CD125 Protein is expressed from HEK293 with His tag at the C-Terminus.
It contains Asp18-His339 [Accession | P21183].

分子量大小(Molecular Weight)

The protein has a predicted MW of 37.7 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22μm filtered solution in 20mM Tris, 500mM NaCl (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Mouse IL-5 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Mouse IL-5 R alpha is greater than 95% as determined by SEC-HPLC.

SPR Data

Mouse IL-5 R alpha, His Tag immobilized on CM5 Chip can bind Mouse IL-5, His Tag with an affinity constant of 0.495 μM as determined in SPR assay (Biacore T200).

背景(Background)

Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.

分子别名(Synonyms)

CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560

文献(References)

(1) Garcia G , Taille C , Laveneziana P , et al. Anti-interleukin-5 therapy in severe asthma[J]. European Respiratory Review, 2013, 22(129):251-257.