ILA-CM14RB | 价格

ILA-CM14RB-100μg / 询价

ILA-CM14RB-500μg / 询价

ILA-CM14RB-500μgx2 / 询价

Biotinylated Cynomolgus IL-4 R alpha/CD124 Protein (Primary Amine Labeling)

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Biotinylated Cynomolgus IL-4 R alpha/CD124 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-terminus.
It contains Met26-Arg232 [Accession | G7Q0S7].

分子量大小(Molecular Weight)

The protein has a predicted MW of 24.84 kDa. Due to glycosylation, the protein migrates to 48-68 kDa based on Bis-Tris PAGE result.

纯度(Purity)

>95% as determined by Bis-Tris PAGE
>95% as determined by HPLC

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Biotinylated Cynomolgus IL-4 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Biotinylated Cynomolgus IL-4 R alpha is greater than 95% as determined by SEC-HPLC.

ELISA Data

Immobilized Cynomolgus IL-4, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Cynomolgus IL-4 R alpha, His Tag with the EC50 of 0.37μg/ml determined by ELISA (QC Test).

背景(Background)

Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family. The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.

分子别名(Synonyms)

CD124; IL-4 R alpha; IL-4R subunit alpha; IL4R; IL-4Ra; IL4RACD124

文献(References)

(1) Ghoreschi K , Thomas P , Breit S , et al. Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease[J]. Nature Medicine, 2002, 9(1):40-46.