IL5-HM22R | 价格

IL5-HM22R-100μg / 询价

IL5-HM22R-500μg / 询价

IL5-HM22R-500μgx2 / 询价

Human IL-5 R alpha/CD125 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human IL-5 R alpha/CD125 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-terminus.
It contains Asp21-Trp342 [Accession | Q01344-1].

分子量大小(Molecular Weight)

The protein has a predicted MW of 62.73 kDa. Due to glycosylation, the protein migrates to 75-95 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Supplied as 0.22 μm filtered solution in PBS (pH 7.4).

存储(Storage)

Valid for 12 months from date of receipt when stored at -80°C.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Human IL-5 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Human IL-5 R alpha is greater than 95% as determined by SEC-HPLC.
ELISA Data
Immobilized Human IL-5, His Tag (Cat. IL5-HM101) at 1μg/ml (100μl/well) on the plate. Dose response curve for Human IL-5 R alpha, hFc Tag with the EC50 of 8.0ng/ml determined by ELISA. (QC Test)
背景(Background)

Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5.

分子别名(Synonyms)

CD125; CDw125CD125; HSIL5R3; IL-5 R alpha; IL-5R subunit alpha; IL5R; IL5RA; IL-5Ra; MGC26560

文献(References)

(1)Garcia G , Taille C , Laveneziana P , et al. Anti-interleukin-5 therapy in severe asthma[J]. European Respiratory Review, 2013, 22(129):251-257.