IL4-MM101 | 价格

IL4-MM101-100μg / 询价

IL4-MM101-500μg / 询价

IL4-MM101-500μgx2 / 询价

Mouse IL-4 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Mouse IL-4 Protein is expressed from HEK293 with His tag at the C-terminus.
It contains His21-Ser140 [Accession | P07750].

分子量大小(Molecular Weight)

The protein has a predicted MW of 15.17 kDa. Due to glycosylation, the protein migrates to 20-30 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC

内毒素(Endotoxin)

Less than 0.1 EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE
Mouse IL-4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
SEC-HPLC
The purity of Mouse IL-4 is greater than 95% as determined by SEC-HPLC.
SPR Data
Mouse IL-4 R alpha, His Tag (Cat. ILA-MM14R) immobilized on CM5 Chip can bind Mouse IL-4, His Tag with an affinity constant of 21.13 pM as determined in SPR assay (Biacore S200).
背景(Background)

Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor.

分子别名(Synonyms)

IL4; IL-4; interleukin 4; MGC79402; pitrakinra; B cell growth factor 1; BCDF; BCGF1; BCGF-1; binetrakin; BSF1; BSF-1; BSF-1

文献(References)

(1)Ghoreschi K , Thomas P , Breit S , et al. Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease[J]. Nature Medicine, 2002, 9(1):40-46.

Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.