IL2-HM219 | 价格

IL2-HM219-100μg / 询价

IL2-HM219-500μg / 询价

IL2-HM219-500μgx2 / 询价

Human IL-23 P19/IL-23A Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human IL-23 P19/IL-23A Protein is expressed from HEK293 with hFc tag at the C-Terminus.
It contains Arg20-Pro189 [Accession | Q9NPF7].

分子量大小(Molecular Weight)

The protein has a predicted MW of 45.43 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.

纯度(Purity)

> 95% as determined by Bis-Tris PAGE

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

制剂(Formulation)

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Bis-Tris PAGE

Human IL-23 P19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

背景(Background)

IL-23 is a heterodimeric cytokine composed of a unique p19 subunit and a common p40 subunit is shared with IL-12. IL-23 promotes the inflammatory response by inducing the expansion of CD4(+) cells producing IL-17.

分子别名(Synonyms)

IL-23 P19; IL-23A; IL-23-A; IL-23p19; IL23p19; SGRF

文献(References)

Mise-Omata S, Kuroda E, Niikura J, Yamashita U, Obata Y, Doi TS. A proximal kappaB site in the IL-23 p19 promoter is responsible for RelA- and c-Rel-dependent transcription. J Immunol. 2007 Nov 15;179(10):6596-603. doi: 10.4049/jimmunol.179.10.6596. PMID: 17982049.