IL1-HM2RC-100μg / 询价
IL1-HM2RC-500μg / 询价
IL1-HM2RC-500μgx2 / 询价
Human IL-17Rc Protein
Recombinant Human IL-17Rc Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Leu21-Arg467 [Accession | NP_703190.2].
The protein has a predicted MW of 76.2 kDa. Due to glycosylation, the protein migrates to 95-135 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1 EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
IL-17 receptor C; IL-17RC; IL17Rhom; IL-17RL; ZcytoR14
(1) You Z, Dong Y, Kong X, Zhang Y, Vessella RL, Melamed J. Differential expression of IL-17RC isoforms in androgen-dependent and androgen-independent prostate cancers. Neoplasia. 2007 Jun;9(6):464-70. doi: 10.1593/neo.07109. PMID: 17603628; PMCID: PMC1899256.
