FSF-MM615-100μg / 询价
FSF-MM615-500μg / 询价
FSF-MM615-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Mouse TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Ala61-Leu252 [Accession | Q5UBV8]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result. |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 0.1 EU per μg by the LAL method. |
制剂(Formulation)
|
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
重构方法(Reconstitution)
|
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions. |
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Mouse TNFSF15 Protein is expressed from HEK293 with monomeric Fc tag at the N-terminus.It contains Ala61-Leu252 [Accession | Q5UBV8].
The protein has a predicted MW of 45.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 0.1 EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
TL1A and its functional receptor DR3 are members of the TNF/TNFR superfamilies of proteins.TL1A and DR3 are abundantly localized at inflamed intestinal areas of patients with IBD and mice with experimental ileitis or colitis and actively participate in the immunological pathways that underlie mucosal homeostasis and intestinal inflammation.Recently, an important role was demonstrated for TL1A/DR3 as potential mediators of intestinal fibrosis that is associated with the presence of gut inflammation.
TL1A; VEGI-251; TNFSF15; TL1; VEGI; VEGI192A
(1) Valatas V, Kolios G, Bamias G. TL1A (TNFSF15) and DR3 (TNFRSF25): A Co-stimulatory System of Cytokines With Diverse Functions in Gut Mucosal Immunity. Front Immunol. 2019 Mar 27;10:583. doi: 10.3389/fimmu.2019.00583. PMID: 30972074; PMCID: PMC6445966.
FSF-MM615-100μg / 询价
FSF-MM615-500μg / 询价
FSF-MM615-500μgx2 / 询价
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