货号价格

LIL-HM4A2-100μg / 询价

LIL-HM4A2-500μg / 询价

LIL-HM4A2-500μgx2 / 询价

Human LILRA2/CD85h/ILT1 Protein

产品信息(Product Info)
表达区间及表达系统(Source)

Recombinant Human LILRA2/CD85h/ILT1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Gly24-Asn449.[Accession | Q8N149-1]

分子量大小(Molecular Weight)

The protein has a predicted MW of 49.9 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

内毒素(Endotoxin)

Less than 1EU per μg by the LAL method.

纯度(Purity)

> 95% as determined by Tris-Bis PAGE

制剂(Formulation)

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

重构方法(Reconstitution)

Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

存储(Storage)

-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3-6 months after reconstitution.
2-8°C for 2-7 days after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

产品数据(Assay Data)
Tris-Bis PAGE

Human LILRA2 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

背景(Background)

LILRA2, also known as ILT1, CD85h, and LIR7, is an approximately 70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA2 consists of a 426 amino acid (aa) extracellular domain (ECD) with 4 Ig-like domains, a 21 aa transmembrane segment, and a 13 aa cytoplasmic tail. LILRA2 is part of the innate immune responses against microbial infection.

分子别名(Synonyms)

CD85h; ILT1; ILT-1; ILT1CD85H; LILRA2; LIR7

文献(References)

(1)Lu H K , Ainslie M , Yasumi E , et al. LILRA2 Selectively Modulates LPS-Mediated Cytokine Production and Inhibits Phagocytosis by Monocytes[J]. PLoS ONE, 2012, 7(3):e33478-.