CEA-HM103-100μg / 询价
CEA-HM103-500μg / 询价
CEA-HM103-500μgx2 / 询价
表达区间及表达系统(Source)
|
Recombinant Human CEACAM-3/CD66d Protein is expressed from HEK293 with His tag at the C-terminus.It contains Lys35-Gly155 [Accession | P40198-1]. |
分子量大小(Molecular Weight)
|
The protein has a predicted MW of 14.19 kDa. Due to glycosylation, the protein migrates to 17-27 kDa based on Bis-Tris PAGE result. |
纯度(Purity)
|
> 95% as determined by Bis-Tris PAGE |
内毒素(Endotoxin)
|
Less than 1EU per μg by the LAL method. |
制剂(Formulation)
|
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
重构方法(Reconstitution)
|
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions. |
存储(Storage)
|
-20 to -80°C for 12 months as supplied from date of receipt. |
Recombinant Human CEACAM-3/CD66d Protein is expressed from HEK293 with His tag at the C-terminus.It contains Lys35-Gly155 [Accession | P40198-1].
The protein has a predicted MW of 14.19 kDa. Due to glycosylation, the protein migrates to 17-27 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac.
CEACAM3; CD66d; CGM1; CEA;
Schmitter T, Pils S, Sakk V, Frank R, Fischer KD, Hauck CR. The granulocyte receptor carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) directly associates with Vav to promote phagocytosis of human pathogens. J Immunol. 2007 Mar 15;178(6):3797-805. doi: 10.4049/jimmunol.178.6.3797. PMID: 17339478.
CEA-HM103-100μg / 询价
CEA-HM103-500μg / 询价
CEA-HM103-500μgx2 / 询价
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